Hundreds of years after the events in Against the Fall of Night, Alvin and Seranis are working to repopulate the Earth with original species resurrected from a library of ancient genetic information. Among these resurrected beings is Cley, a Cro-Magnon and sole survivor of her tribe. Cley joins forces with Alvin and a large, intelligent rodent named Seeker to eliminate the threat from the Mad Mind once and for all — and clear the way for life in the Solar System to thrive.

Beyond the Fall of Night is an authorized sequel to Arthur C. Clarke's classic science fiction novel Against the Fall of Night, written by acclaimed science fiction author and astrophysicist Gregory Benford.